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noun(von Wil-le-brand disease)a genetic blood disorder marked by prolonged, excessive, or abnormal bleeding that commonly results in recurrent nosebleeds, heavy menstrual flow, and bleeding from the gums, is caused by deficient or defective von Willebrand factor, and typically occurs in a mild form that is less serious than hemophilia
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noun(von Wil-le-brand disease)a large glycoprotein clotting factor circulating in blood plasma that mediates platelet adhesion to collagen at sites of vascular injury, that binds to and protects factor VIII from degradation, and that is deficient or defective in individuals affected with von Willebrand disease —called also VW factor
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biographical name(von Wil-le-brand disease)Wernher
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biographical name(von Wil-le-brand disease)Adolf 1835—1917 German chemist
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biographical name(von Wil-le-brand disease)1098—1179 German mystic and composer
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biographical name(von Wil-le-brand disease)Julius 1857—1940 Austrian neurologist and psychiatrist
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biographical name(von Wil-le-brand disease)circa 1170—circa 1230 German minnesinger and poet
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biographical name(von Wil-le-brand disease)circa 1170—circa 1220 German poet and minnesinger