a primary sore or ulcer at the site of entry of a pathogen (as in tularemia); especially : the initial lesion of syphilis
chancre
noun(chan-cre)
chancroid
chancre
noun(chan-cre)
a venereal disease caused by a bacterium (Hemophilus ducreyi) and characterized by chancres unlike those of syphilis in lacking firm indurated margins —called also soft chancre